Plenary Session 1 • Advances in Cobalamin Research

New insights into cobalamin absorption and metabolism using accelerator mass spectrometry
Ralph Green (Davis, CA/US)

Vitamin B12 and its binding proteins
Ebba Nexo (Aarhus/DK)

Advances In Cobalamin Research: Targeting The Transcobalamin Receptor TCblR/CD320
Edward Quadros (New York/US)

Insights into functional cobalamin deficiency: the MMACHC proteome
Luciana Hannibal (Cleveland/US)

Plenary Session 2 • Transsulfuration and Gluathione metabolism

New insights into cobalamin absorption and metabolism using accelerator mass spectrometry
Ruma Banerjee (Ann Arbor, US)

Hydrogen sulfide and oxygen sensing
Kenneth R. Olson (South Bend/US)

Inflammatory markers, kynurenines and vitamin B6 in relation to chronic disease
Simone Eussen (Bergen/NO)

Cystathionine gamma-lyase dependent H2S formation in perivascular adipose tissue in experimental metabolic syndrome
Jerzy Beltowski (Lublin/PO)

Plenary Session 3 • Vitamin B6 and Riboflavin

Vitamin B-6 and folate affect the association between MAT1A variants and hypertension, stroke, and markers of DNA damage
Chao Qiang Lai (Boston/US)

Role of Vitamin B6 and its Metabolite in Ca2+-handling and Cardiac Function
Naranjan S. Dhalla (Winnipeg, CA)

Riboflavin as a determinant of iron status
Hilary Powers (Sheffield/UK)

Plenary Session 4 • B-Vitamins and age-associated diseases: Neurology

Antiepileptic drugs and B-Vitamins: epidemiological and electrophysiological data
Michael Linnebank (Zurich/CH)

Normal prions as a new target of cobalamin deficiency in rat CNS
Guiseppe Scalabrino (Milan/IT)

Mechanisms of Neurological complications in HHCY
Aron Troen (Rehovot/IL)

Plenary Session 5 • B-Vitamins and age-associated diseases: Osteoporosis

Osteoporosis – New Diagnostic and Clinical Aspects
Markus Herrmann (Penrith/AU)

Altered bone structure and decreased bone formation, the role of B-vitamins and homocystein
Jörg Holstein (Homburg/Saar/DE)

Homocysteine mediated decrease in bone blood flow and remodeling: Role of folic acid
Neetu Tyagi (Louisville/US)

Homocysteine effect on osteoporosis
Eleftherios Paschalis (Vienna/AT)

Plenary Session 6 • B-Vitamins & Diabetes and renal dysfunction & CVD

Disturbance of thiamine metabolism in diabetes and the development and treatment of diabetic vascular complications
Paul J. Thornalley (Penrith/AU)

Intracellular cobalamin status in diabetes and  polyneuropathy
Rima Obeid (Homburg/Saar/DE)

Mechanisms of H2S signalling in hemodialysis
Alessandra Perna (Naples/IT)

Plenary Session 7 • B-Vitamins and Choline: Pre- and postnatal Health

Molecular mechanisms of B-vitamin deficiency in neural tube defects and other birth defects
Henk Blom (Amsterdam/NL)

Folic acid supplementation during pregnancy and cancer risk in the offspring
Young-In Kim (Toronto/CA)

Genetic and nutritional variation in one-carbon metabolism influences reproductive outcomes
Rima Rozen (Montreal/CA)

Plenary Session 8 • Nutrients as methyl donors

Betaine, both a methyl donor and an osmolyte
Michael Lever (Christchurch/NZ)

Metabolic and Functional Effects of Choline in Cystic Fibrosis
Sheila Innis (Vancouver/CA)

Choline intake and cancer risk: epidemiologic studies
Eunyoung Cho (Boston/US)

Plenary Session 9 • Advances in Choline Research

Choline metabolism is related to endoplasmiceticulim stress response in vascular- and metabolic disease
Gerd Schmitz (Regensburg/DE)

Choline and the brain
Jan Blusztajn (Boston/US)

Fatty acid metabolism in choline and methionine deficiency
David McFarland (Dundee/UK)

Choline - containing phospholipids on brain functional pathways
Seyed K. Tayebati (Camerino/IT)

Plenary Session 10 • B-Vitamins and choline: Alcohol and liver function

Methionine metabolism in liver diseases
Kusum Kharbanda (Omaha/US)

B-Vitamin Dependent Methionine Metabolism in Pathogenesis, Prevention, and Treatment of Alcoholic Liver Disease
Charles Halsted (Davis/US)

Choline as a treatment for fetal alchohol spectrum disorders
Jennifer Thomas (San Diego/US)

Homocysteine in alcoholic liver disease
Donald Jacobsen (Cleveland/US)

Plenary Session 11 • (Epi)genetics, Diseases: The role of nutrients

Epigenetics and Choline
Steven Zeisel (Kannapolis/US)

Epigenomics effects of deficiency in methyl donors
Jean-Louis Guéant (Nancy-Vandoeuvre/FR)

The role of epigenetics in neurodegeneration
Andrea Fuso (Roma/IT)

Varied maternal choline intake in humans alters metabolic, epigenomic and epigenetic marks
Marie Claudill (Ithaca/US)

Plenary Session 12 • Concerns on B-Vitamin supplementation

Folate Intake Modulates Carcinogenesis: Mechanisms and Consequences
Joel Mason (Boston/US)

Renal function determines response to B vitamin therapy for homocysteine
David Spence (London/CA)

Diet as source of methyl donors nutrients: from raw to "ready-to-eat" foods
Gregorio Varela Moreiras (Boadilla del Monte/ES)

Plenary Session 13 • Molecular mechanisms

Cellular damage by homocysteine; the role of protein N-homocysteinylation
Hieronim Jakubowski (Newark/US)

Homocysteine and ADMA Influence Cerebrovascular and Myocardial Function through distinct mechanisms
Steven Lentz (Iowa/CA)

Folic acid and homocysteine: from coronary vasodilation to neuroprotection
Dragan Djuric (Belgrade/RS)

Immune activation and moderate hyperhomoysteinemia
Dietmar Fuchs (Innsbruck/AT)

Further speaker

Kinetic Modelling of Storage Effects on Biomarkers Related to B-vitamin Status and One-Carbon Metabolism
Per Magne Ueland (Bergen/NO)

Last update: November 17, 2011